The Helltide event is one of Diablo IV gold the best places to farm Horadric Vials. During a Helltide, high-threat zones spawn more elite enemies and bosses, which significantly increases your odds of earning vials. Additionally, there are several mechanics within the Helltide that can boost your vial collection:
Collect Anomalous Embers to open special chests that often contain vials and other valuable loot.
Raise your threat level by staying active in Helltide zones—this causes stronger enemies to spawn, with better drop potential.
Summon and defeat the Bloody Maiden using Baneful Hearts for a guaranteed elite encounter with high chances of Horadric rewards.
Tree of Whispers and Grim Favors
Completing Grim Favor quests and turning them in to the Tree of cheap Diablo 4 gold Whispers is another efficient method. These activities reward players with caches that often contain Horadric Vials, along with crafting materials, gear, and experience.